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Groundbreaking technique developed to measure oxygen in deep-sited tumor, brain

Led by Harold Swartz, MD, PhD, the team published their groundbreaking progress on the decades-old conundrum of how to measure oxygenation in deep-sited tissue in a paper titled, "Deep-Tissue Oxygen...

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Origins of colorectal cancer tumor cells traced

The scientists employed a "Big Bang" model of human colorectal cancer growth similar to the theory that the universe started from a single point and exploded outward. The team was led by Keck faculty...

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In lab research, team halts NASH liver damage

In a study published in Molecular Metabolism, Saint Louis University researchers have tested in an animal model a promising drug candidate that stopped fatty liver disease from progressing to the stage...

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New target for prostate cancer treatment discovered

Prostate cancer is the second most common cancer in American men, after skin cancer, according to the American Cancer Society (ACS). The ACS projects more than 27,000 deaths from prostate cancer in...

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Stem cells lurking in tumors can resist treatment

New research proves that the threat posed by cancer stem cells is more prevalent than previously thought. Until now, stem cells had been identified only in aggressive, fast-growing tumors. ...

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Concurrent chemoradiation treatment at high-volume facilities improves...

Lung cancer is the leading cause of cancer related death in the US with 159,000 deaths and 224,000 diagnoses each year, with NSCLC accounting for 85% of the cases. The stage of lung cancer is...

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Naproxen plus acid blocking drug shows promise in preventing bladder cancer

A new study suggests there may be ways to reduce these dangerous side effects. Collaborators from the University of Michigan, the National Cancer Institute and the University of Alabama looked at...

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MRI based on a sugar molecule can tell cancerous from noncancerous cells

The MRI technique, so far tested only in test tube-grown cells and mice, is described in a report published March 27 in the online journal Nature Communications. ...

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Golgi trafficking controlled by G-proteins

The study is reported online April 9 in Developmental Cell. "Our work provides the first direct evidence that G proteins are signaling on membranes inside cells, not just at the cell surface as has...

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New approach to treat drug-resistant HER2–positive breast cancer

The discovery, published in the journal CELL Reports, provides the experimental evidence for the potential development of a novel combination therapy for HER2-positive breast cancer. The combination...

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